Supplemental files from Endogenous glucose production in patients with glycogen storage disease type Ia estimated by oral D [6,6-2H2]-glucose
Version 3 2023-07-26, 20:03
Version 2 2023-07-26, 19:50
Version 1 2023-07-26, 19:48
dataset
posted on 2023-07-26, 20:03 authored by Alessandro Rossi, Maaike H. Oosterveer, Theo H. van Dijk, Aycha Bleeker, Martijn Koehorst, David Weinstein, Barbara M. Bakker, Terry G. J. Derks<p> Supplemental file 1. <strong>Calculated </strong><em><strong>M</strong></em><sub><em><strong>2</strong></em></sub><strong> curve in study participants during glucose-SIB test 1 (blue), glucose-SIB test 2 (red) and glucose-SIB test 3 (green).</strong> Less than 25% decrease in concentration between the peak and the last time point were observed in subject 008 (glucose-SIB test 1), subject 019 (glucose-SIB test 2) and subject 020 (glucose-SIB test 2) disqualifying these data for computational analysis.</p>
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<p><strong> Supplemental file 2. Capillary glucose concentrations in study participants during glucose-SIB test 1 (A) and 2 (B).</strong></p>
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<p><strong>Supplemental file 3. Calculated model parameters in the study participants. </strong>Data in italics were excluded from calculations. (A) GSDIa patients with attenuated phenotype. (B) GSDIa patients with a severe phenotype. (C) Healthy volunteers.</p>
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