ppat.1011983.s004.xlsx (15.07 kB)
Summary of cytokine multiplex data.
dataset
posted on 2024-01-25, 18:46 authored by Miguel A. B. Mercado, Qiang Li, Charles M. Quick, Yejin Kim, Rachel Palmer, Lu Huang, Lin-Xi LiWT and Bhlhe40-/- mice were infected intravaginally with 1×105 C. muridarum. Cytokine levels in the supernatants of ex vivo cultures of DLN and FRT cells as measured at 10 dpi using a Multiplex cytokine/chemokine array.
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regulatory type 1protein basic helixfemale reproductive tractdiv >< pwhereas wt cd410r increased cd4key molecular driverheightened bacterial burdens>< sup ><decreased polyfunctional cd4>- deficient cd4exhibited severe defectschlamydia muridarum chlamydia polyfunctional responseskey regulator>mice deficientusing singletcr profilingsignificant enrichmentpartially rescuedmarked increaseintracellular bacteriumhost immunitygenetic ablationfunctional blockadedifferentiation trajectorycell signaturescell responsescell polyfunctionalitycell differentiationbacterial controlautoimmune diseases
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