ppat.1012031.s013.xlsx (67.68 kB)
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posted on 2024-03-01, 21:05 authored by Jakob L. Sprague, Tim B. Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L. Priest, Antzela Tsavou, Gianni Panagiotou, Julian R. Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard HubeAll data used to generate graphs for main text and supplementary figures.
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process remain unclearmicrobial mechanisms behindhuman mucosal surfacesfull virulence potentialfrequently causes infectionsdiv >< pcertain predisposing conditionsopportunistic fungal pathogenpeptide toxin candidalysinintestinal epithelial barrierfungal zinc acquisitionintestinal epithelial cellsmediated barrier protectionrestrict fungal translocationcandida albicans iecs limits candidalysiniecs counteract damagecell damage mediatedintestinal barrieridentified fungalalbicans mediated damagenutrient acquisitioncells servesmediated maintenanceece1 c cell damageusing dualtranslocation acrosstnf signalingspecific responserna sequencingmediates maintenancemain sourceharmless commensalencoding genedisseminated candidiasisdata suggestcell junctions
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