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posted on 2022-05-12, 18:45 authored by Bian LiBian Li, Dan M. Roden, John A. Capra

This item hosts the source code and all source data for reproducing the figures in the main text and supplementary text of the paper entitled: The 3D mutational constraint on amino acid sites in the human proteome.

Funding

The Evolution of Gene Regulation and Human Disease

National Institute of General Medical Sciences

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Personalized Structural Biology: Enabling Exome Interpretation in Undiagnosed Diseases

United States National Library of Medicine

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Biophysical Insights into and Probabilistic Interpretation of Cardiac Ion Channel Variants of Uncertain Significance

American Heart Association

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History