figshare.zip (72.37 MB)
Single cell analysis of gene expression in the substantia nigra pars compacta of a pesticide-induced mouse model of Parkinson’s disease
dataset
posted on 2022-02-18, 18:36 authored by Arshad H. Khan, Lydia Lee, Desmond SmithDesmond Smith"Single cell analysis of gene expression in the substantia nigra pars compacta of a pesticide-induced mouse model of Parkinson’s disease"
Arshad H. Khan1, Lydia K. Lee2, Desmond J. Smith1,3
1 Department of Molecular and Medical Pharmacology
David Geffen School of Medicine, UCLA
Los Angeles, CA 90095-1735
2 Department of Obstetrics and Gynecology
David Geffen School of Medicine, UCLA
Los Angeles, CA 90095-6928
3 To whom correspondence should be addressed:
Department of Molecular and Medical Pharmacology
David Geffen School of Medicine, UCLA
Box 951735, 23-151A CHS
Los Angeles, CA 90095-1735
Email: DSmith@mednet.ucla.edu
"Words" folder contains pdfs of the Manuscript and Supplementary Data.
"Supplementary_Tables" folder contains results from single cell RNA-seq (scRNA-seq) analysis.
"Behavior" folder contains data from pole and dot removal tests.
"Single_cell_RNA_data" folder contains scRNA-seq data from substantia nigra pars compacta (SNpc) of mice treated with combined dosing of the pesticides maneb and paraquat (MNPQ) or saline. Raw and filtered output from 10X Genomics Cell Ranger pipeline provided.
