Seurat SmartSeq A.10-12

seurat v3 object

ASSAYS:

RNA: mRNA expression data

DIMENSIONALITY REDUCTION

projected: Data was projected on the main AML dataset from Cohorts A and B.

scanorama: Data was integrated with Scanorama, using the patient as Batch key

umap: umap computed from Scanorama components

METADATA

patient: Patient

ct: Projected cell type (Triana et al., 2021)

ct_simple: Simplified projected celltype

pseudo_myel: Projected myeloid pseudotime (Triana et al., 2021)

proj_cluster: Projected cluster from main AML dataset 

dormancy_score: score assessing the dormancy of cells based on Zhang 2021 and Cabezas-Wallscheid 2017 gene lists.