pbio.3001324.s007.xlsx (52.24 kB)
S1 Data -
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posted on 2021-06-30, 17:37 authored by Markus K. Klose, Paul J. Shaw(A, B) Sleep in minutes/hours for 0-, 1-, and 3-day-old flies maintained on a 12:12 LD schedule. (C–E) FRET ratio measurements in Pdf-GAL4>UAS-Epac1 flies in response to DA, Oa, and PDF. (F) The amplitude of l-LNv responses to PDF. DA, dopamine; FRET, Förster Resonance Energy Transfer; LD, light:dark; l-LNv, large ventral lateral neuron; Oa, octopamine; PDF, pigment dispersing factor.
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Downstream circuitscell surface receptorsreceptor respecification phenomenaPDFR2 dopamineSleep drive reconfigures wake-promo...activity-dependent additioncAMP response element-binding proteinventrolateral clock neuronsventrolateral neuronstranscriptional regulator nejirereceptor respecificationclock neurons influencedemandDAfactor receptoradaptive behavior Circadian rhythmssculpt circuit functionmating successHebbian plasticityCREBBPRecent evidence
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