pntd.0009602.s001.xlsx (18.8 kB)
Response in the trypomastigotes assay at 48 and 72 hours.
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posted on 2021-07-16, 17:44 authored by Juan Cantizani, Pablo Gamallo, Ignacio Cotillo, Raquel Alvarez-Velilla, Julio MartinpIC50 = —log10IC50 in molar units. Data from pIC50 values for CYP51 assay have been formerly reported [1].
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curve descriptorsAutomated data reductioncompounds collectionBNZGSK 1.8animal modelsCurrent chemotherapeuticsLatin Americacompound optimisation programsNIFscreening campaigndata analysismigration flowsPCAnitroaromatic compoundssuboptimal efficacycompound setsGSK Chagas Box Chagas diseasedrug discovererscombo therapyantifungal azolesefficacy outcomesHTS campaignChagas disease drug discoveryguide navigationshow efficacycompound selectionTrypanosoma cruzihigh-throughput compoundCYPbench modelsGSK Chagas Box
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