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Raw voltage and current traces for current-voltage (IV) relationships for cochlear nucleus neurons.

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posted on 2019-09-17, 21:19 authored by Paul ManisPaul Manis, Michael R. Kasten, Ruili Xie
Whole-cell tight seal current-clamp recordings from neurons in brain slices of mouse cochlear nucleus. These data are the responses to series of current steps (100 and 500 ms in duration), used to derive measures of intrinsic excitability, including input resistance, resting membrane potential, time constants, spike shape parameters, coefficient of variation of spike rate, and adaptation. The data were analyzed using the package ephysanalysis (https://github.com/pbmanis/ephysanalysis). The raw data here are in NWB
format(https://neurodatawithoutborders.github.io/pynwb), and have been extracted from the main dataset.

Additional files include the extracted parameters (pickled Pandas database), and Python source files used for the analysis.

See README.md for more details.

Source file CN_LDA.py updated, 9/4/2019. Minor edits to remove unused statements and update docstrings; no change in results.

Preprint: bioRxiv 594713; doi: https://doi.org/10.1101/594713

Funding

R01 DC004551

R01 DC013396

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