ppat.1011449.s009.xlsx (77.49 kB)
Raw peak intensities of various lipid species measured before and after egress in RAP-treated (+RAP) and mock-treated (-RAP) LCAT:2loxPint parasites.
dataset
posted on 2023-06-23, 17:53 authored by Abhinay Ramaprasad, Paul-Christian Burda, Konstantinos Koussis, James A. Thomas, Emma Pietsch, Enrica Calvani, Steven A. Howell, James I. MacRae, Ambrosius P. Snijders, Tim-Wolf Gilberger, Michael J. BlackmanT-test analyses comparing the different groups and normalised spectral peak intensities in each replicate are provided.
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reduced replication ratepreviously demonstrated roleplasmodium falciparum malaria parasite releaselytic effector moleculesparasite proteins dischargedmediated membrane porationfacilitate efficient egressblood stage egresslike proteins simultaneouslydiv >< plike proteinsinvolve membraneegress detectedabnormal egressthus showseveral phosphatidylserineproteomic profilingpf3d7_0629300 ).parasitophorous vacuolelipidomic profilesessential rolesconditional ablationcholesterol acyltransferaseacylphosphatidylglycerol species
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