Table 2.xls (9.5 kB)
Pharmacokinetic parameters in male Syrian golden hamsters following oral administration of 500 mg/kg AT-752.
dataset
posted on 2022-01-24, 18:39 authored by Kai Lin, Steven S. Good, Justin G. Julander, Abbie E. Weight, Adel Moussa, Jean-Pierre SommadossiPharmacokinetic parameters in male Syrian golden hamsters following oral administration of 500 mg/kg AT-752.
History
Usage metrics
Categories
Keywords
serum alanine aminotransferasehigh mortality ratesguanosine nucleotide analogactive triphosphate metabolite70 &# 821131 &# 956yellow fever virusdiv >< p21 days piday 6 pi6 piday 47 dayszoonotic pathogenvivo vitro virus titerviral challengeuntreated groupunexpected outbreaksreduced viremiapromising compoundpreviously identifiedpotent inhibitornormal levelsinfected animalshighest concentrationshamsters infectedfree basefold comparedeffective vaccineeffective concentrationeffective antiviraldouble prodrugclinical developmentanimal tissues4 log1000 mg001 ).
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC