Table 4.xls (5.5 kB)
Paclitaxel transferred to the vessel wall in % of dose on balloon–summarized for drug doses, balloon sizes and arteries.
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posted on 2021-10-29, 17:31 authored by Ole Gemeinhardt, Beatrix Schnorr, Ulrich Speck, Bruno SchellerPaclitaxel transferred to the vessel wall in % of dose on balloon–summarized for drug doses, balloon sizes and arteries.
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statistical significant differencespresent preclinical trialmay reduce medicocurrently marketed productscurrent study investigated2 – 310 ± 36 ± 1two overlapping dcbeconomic cost comparedconventional balloon catheters2 supincreased drug transferincreased drug concentration3 μg ptxdrug coated balloons6 μg ptxnovel dcb coateddrug transfer6 μgincreased ptxreproducibly coatedptx concentration5 μg2x3 μg1x6 μg1x3 μgresidual ptxvessel wallsingle balloonperipheral arteriesdifferent effectivenessballoons resulted178 ).
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