posted on 2021-03-24, 07:15authored byLissiê Lunardi Sbroglio, Viviane Maria Maiolini, Irene Machado Moraes Alvarenga Rabelo, Gabriela Almeida Giraldelli, Luciana Patrícia Tuccori, Rodrigo Guimarães Cunha
Abstract Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user. The patient presented with ulcerated lesions in 2014. Histopathologic analysis revealed amastigotes, and serological test results were positive for leishmaniasis. Systemic therapy with meglumine antimoniate was administered; however, the patient failed to present for follow-up. In 2018, he returned with nasal collapse, and another histopathologic test confirmed MCL. This case illustrates the importance of careful differential diagnosis of skin and mucous ulcers to identify the particular pathology.