Table 3.xls (5.5 kB)
Median months OS and DFS for combined significantly concurrent potentially oncogenic alterations (RNASeq V2 >2-fold and/or gene amplification and/or mutation as noted) for RTKs and cognate ligands in BCa TCGA dataset (n = 408) [22].
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posted on 2021-07-22, 17:50 authored by Young H. Lee, Molly M. Lee, Dinuka M. De Silva, Arpita Roy, Cara E. Wright, Tiffany K. Wong, Rene Costello, Oluwole Olaku, Robert L. Grubb III, Piyush K. Agarwal, Andrea B. Apolo, Donald P. BottaroMedian months OS and DFS for combined significantly concurrent potentially oncogenic alterations (RNASeq V2 >2-fold and/or gene amplification and/or mutation as noted) for RTKs and cognate ligands in BCa TCGA dataset (n = 408) [22].
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BCa cell linesBCa-derived cell linesoncogenic TK pathway-related altera...receptor tyrosine kinasespatient survivalAXLMany TK pathwaysCSF9 EMT transcriptional activatorsCo-occurring alterationsBCa patient survival1RTCGA casesEMT transcriptional activatorsCancer Genome AtlasMSTbladder Comprehensive characterizationsTK inhibitor usegroup 1 TKs
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