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Lipidomic measurement of TG species concentrations during OFTT.

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posted on 2021-09-20, 17:46 authored by Sumeet A. Khetarpal, Cecilia Vitali, Michael G. Levin, Derek Klarin, Joseph Park, Akhil Pampana, John S. Millar, Takashi Kuwano, Dhavamani Sugasini, Papasani V. Subbaiah, Jeffrey T. Billheimer, Pradeep Natarajan, Daniel J. Rader

Concentrations of plasma TG species were measured by LC-MS as described in the Materials and Methods. TG species were measured from plasma of WT vs Lipg-/- mice after overnight fasting and 7 hours after OFTT with olive oil gavage (10 μl/g). Each column under a group header (WT or Lipg-/-) corresponds to an individual mouse. Fold Difference corresponds to the ratio of mean concentrations for a given TG species from Lipg-/- vs WT mice for a given timepoint. P-value corresponds to comparison of WT vs Lipg-/- mice for a given timepoint by student’s unpaired T-test.

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