posted on 2021-03-24, 07:27authored bySilméia Garcia Zanati Bazan, Gilberto Ornellas de Oliveira, Caroline Ferreira da Silva Mazeto Pupo da Silveira, Fabrício Moreira Reis, Karina Nogueira Dias Secco Malagutte, Lucas Santos Nielsen Tinasi, Rodrigo Bazan, João Carlos Hueb, Katashi Okoshi
Abstract Hypertrophic cardiomyopathy (HCM) is the most common heart disease with a genetic origin, and its main characteristic is left ventricular hypertrophy that occurs in the absence of other conditions that trigger this change. HCM may present from asymptomatic forms to manifestations of sudden cardiac death and severe heart failure. Contemporary high-resolution imaging methods and more accurate clinical scores have been used and developed to provide a prognostic assessment and adequate functional assessments, as well as to allow for the stratification of clinical severity. These aspects will be addressed in this review, along with other classic topics inherent to the study of this disease.