HDL GWAS

Created on 24 Aug 2023 - 09:49 by Fergus Hamilton

This data includes the GWAS of HDL particle counts performed in UK Biobank on the full Nightingame NMR sample. Full details are in the paper. The scale is of 1 SD change in each component.

The components include:

Small HDL (S_HDL_P)

Medium HDL (M_HDL_P)

Large HDL (L_HDL_P)

Extra Large HDL (XL_HDL_P)

Total HDL (HDL_P)

HDL without small componenet (HDL_WO_S_HDL)

The GWAS was performed using regenie, and therefore the columns represent that from regenie (https://rgcgithub.github.io/regenie/options/).

The GWAS was performed adjusted for age, sex, and the first 10 genetic principle components. We only included European Ancestry participants