Gene Candidate Prioritizations In Genetic Diseases With GLOWgenes (www.glowgenes.org)

Every directory contains the output of GLOWgenes for a disease.

- The disease name is in the directory name itself

- The gene panels for every disease were downloaded from https://panelapp.genomicsengland.co.uk/panels/

- GLOWgenes was run using as input the gene panel provided by PanelApp

- GLOWgenes results:

- GLOWgenes_prioritization_Random.txt is the file with the genes ranked based on their association to the gene panel, prioritization goes from 1 to the largest number

- Files like GLOWgenes_NetworkName_KnowledgeCategory.txt (e.g. GLOWgenes_Reactome_PATHWAYS.txt) contaisn prioritizations for every network

If you use GLOWgenes prioritization, please cite us: https://www.medrxiv.org/content/10.1101/2022.10.07.22280759v2.full