Ampicillin concentration dependence of the fraction of VBNC, persister, susceptible non lysed cells, and lysed cells. Persister fractions were measured via both our newly developed single-cell approach and the standard persister assay based on colony forming units (CFU) measurements. However, the CFU method does not allow measuring the fraction of VBNC, susceptible non lysed cells, and lysed cells.
Funding
Royal Society Research Grant (RG140203); Welcome Trust ISSF (097835/Z/11/Z); BBSRC award BB/1024631/1