Fig. 4e

B16F10 cells expressing MICA*001 were engrafted, s.c., into C57BL/6 mice. 4 days later, when tumors reach 150 mm³, mice were randomized to six groups and treated once weekly for three consecutive weeks with 0.1 mg/kg, 0.25 mg/kg or 0.5 mg/kg MICAB1 PBD1G-ADCs or IC-PBD1G. Kaplan–Meier curves showing mouse survival (n=12 per group). Mantel-Cox test, **** p<0.0001 (0.5 mg/kg and 0.25 mg/kg) and ***p<0.001 (0.1mg/kg). Right panels: Cured mice (n=9) and naïve mice (n=10) were re-challenged s.c. with B16F10 expressing MICA*001 on one flank. Some cured mice (n=4) were not re-challenged and monitored for eventual tumor regrowth