Dataset periodontitis y2021m02
Description and susceptibility of periodontopathic bacteria with severe chronic periodontitis among a group of Peruvian patients: A pilot study
ABSTRACT
Background: Severe periodontal disease is highly prevalent worldwide, affecting 20 % of the population between the ages of 35 and 44 years old. The etiological epidemiology in Peru is scarce, even though some studies describe a prevalence of 48.5 % of periodontal disease in the general population. Periodontitis is one of the most prevalent oral diseases associated with site-specific changes in the oral microbiota and it has been associated to socioeconomic state. This study aimed to determine the etiology and resistance profile of bacteria identified in a group of patients with chronic severe periodontitis.
Methods: Six subgingival plaque samples were collected from eight patients with chronic severe periodontitis. Bacterial identification was carried out by an initial culture, PCR amplification and subsequently DNA sequencing. We evaluated the antibiotic susceptibility by disk diffusion method.
Conclusions: Bacterial species of importance medical were detected in patients with chronic severe periodontitis, especially Rothia dentocariosa, most prevalent in this study. Specific antimicrobial therapy is required to improve the treatment outcomes of patients with periodontal disease and to avoid the development of antibiotic resistance.