Dataset on cardiac structural and functional parameters in TMAO-challenged mouse

The dataset underpinning this investigation is stratified into two distinct subsets: the primary analyzed dataset, conducive to the execution of explicit differential assessments, and the auxiliary corpus of unprocessed raw data, emanating directly from the echocardiographic software, which affords the flexibility for indefinite re-evaluation of cardiac metrics. The curated analyzed dataset comprises a compendium of echocardiographic images and corresponding tabular records for a cohort of 16 murine models subjected to a 6-week dietary regimen enriched with TMAO, in juxtaposition with a control contingent of 18 specimens. Each subject's data portfolio encompasses a sextet of images, inclusive of both M-mode and B-mode echocardiographic projections, captured from the parasternal long-axis and apical four-chamber orientations, alongside a duo of supplementary M-mode representations with embedded cardiac functional parameters. The quantitative structural parameters delineated within the accompanying Excel spreadsheets are derived from a rigorous analysis of M-mode echocardiographic sequences. The acquisition of all image data was facilitated by echocardiographic specialists, ensuring a standardized resolution of 96 dots per inch (dpi), with image dimensions of 1920 pixels in width and 992 pixels in height, thereby ensuring a consistent framework for subsequent image analysis.