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DEGs in tissues with periodontitis in relation to healthy tissues observed in non-diabetic patients and in patients with T2DM concurrently.

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posted on 2024-01-19, 18:51 authored by Poliana Mendes Duarte, Bruno César de Vasconcelos Gurgel, Tamires Szeremeske Miranda, Juliana Sardenberg, Tongjun Gu, Ikramuddin Aukhil

DEGs in tissues with periodontitis in relation to healthy tissues observed in non-diabetic patients and in patients with T2DM concurrently.

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    PLOS ONE

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    whole transcriptome sequencingtype 2 diabetespreliminary findings indicatedifferentially expressed genebiological mechanisms underlyingdistinctive transcriptomic changesdegs confirmed changessignaling pathways associatedsectional study evaluatedingenuity pathway analysisdiv >< pipa also predictedsectional studythree degsipa predictedfunctional pathwaysakt pathwaysdistinctive genesuniquely identifiedtrna splicingptpn2 ptpn13 protein expressionpik3r2 phagosome formationperiodontal healthitga4 il1rn gingival biopsiesfour hundreddhcr24 cholesterol biosynthesiscardiac βcalcrl 6r

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