Table 2.xls (5.5 kB)
Comparison of the number of serum samples that tested positive and negative against each viral NP in the German blood bank and Guinean serum sample sets.
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posted on 2020-10-23, 17:45 authored by Rebecca Surtees, Daniel Stern, Katharina Ahrens, Nicole Kromarek, Angelika Lander, Petra Kreher, Sabrina Weiss, Roger Hewson, Emma K. Punch, John N. Barr, Peter T. Witkowski, Emmanuel Couacy-Hymann, Andrea Marzi, Brigitte G. Dorner, Andreas KurthThe median MFI readings from three technical replicates per sample were analysed in R, and a positive or negative status was assigned to each serum sample. Positivity or negativity was based on a cutoff MFI value that was determined for each viral NP based on the 99th percentile for MFI values in the German blood bank sample set. Statistically significant differences in seroprevalence rates between the two sample sets and odds ratios were calculated using Fisher’s exact test.
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warning systemvirus-like particles5- plex assayreactive high-throughputmultiplex microsphere immunoassayGuinea panelserum samplesreference methodsMMIARift Valley fever virusEBOV NPEbola virusMARV NPanimal serum samples SurveillanceDobrava-Belgrade hantaviruszoonotic reservoirsnon-human primatesantibodytesting seraanimal populationsELISAIIFT88 seraCrimean-Congo haemorrhagic fever virusreactive multiplex microsphere immu...infection statusNP antigensnucleocapsid proteinsGerman blood bankreservoir animalsIgG detectionscreening tool
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