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perinatal_lung.h5ad (548.85 MB)
Cell atlas of the murine perinatal lung
dataset
posted on 2021-05-31, 00:41 authored by Fabio ZaniniFabio Zanini, Cristina M Alvira, David N Cornfield, Stephen QuakeStephen Quake, Xibing Che, Racquel Domingo-GonzalezGene expression counts (raw number of reads) and cell and gene metadata for single cell transcriptomics (plate-based, SmartSeq2) on perinatal murine lungs.
This dataset focuses on immune, endothelial, and mesenchymal cells, but contains a few epithelial cells as well.
There are four time points:
- E18.5: roughly one day before birth
- P1: roughly 24 hours since birth
- P7: 7 days since birth
- P21: 21 days since birth
The P7 timepoints has two conditions:
- normal
- hyperoxia: these mice were exposed to 80% oxygen for the whole week before being euthanized.
Please cite the following papers if you use these data:
Domingo-Gonzales*, Zanini* et al. eLife (2020): https://elifesciences.org/articles/56890
Zanini et al. bioRxiv (2021a): https://www.biorxiv.org/content/10.1101/2021.04.27.441649v1
Zanini et al bioRxiv (2021b): https://www.biorxiv.org/content/10.1101/2021.05.19.444776v1.full
