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pntd.0010777.s003.xlsx (272.44 kB)
BLAST results: S. stercoralis orthologues of the S. ratti E/S proteome.
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posted on 2023-04-17, 17:36 authored by Tegwen Marlais, Jack Bickford-Smith, Carlos Talavera-López, Hai Le, Fatima Chowdhury, Michael A. MilesS. ratti E/S proteomic data from Hunt et al. (2016) was BLAST searched against the S. stercoralis genome-derived proteome using blast+ with e-value 1e-50
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multiple sequence alignmentmany parasitic infectionsdiv >< pdescribe 22 candidates>, giving 13d structure modellingassociated protein familiesfive protein familiesused online predictorsspecific diagnostic assaysrevealed 328 proteinsstrongyloides ratti strongyloides stercoralis strongyloides stercoralis protein coproantigensfive parasitismdiagnostic coproantigens>- specificvalidating curetargeted analysisseven genesscreening priorproteomic datasetsproteomic dataprolyl oligopeptidasepowerful approachpotentially fatalpopulation surveillancepartially dueleast homologyintestinal nematodeinfected stoolinadequate diagnosisimmunosuppressed individualshuman infectionepidemiological datadifferentially expressedcompared phylogeneticallyaspartic peptidaseaccelerate development057 orthologues
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