pbio.3001265.s001.xlsx (8.97 MB)
Anti-SARS-CoV-2 antibody binding patterns do not vary with neutralizing titer.
dataset
posted on 2021-06-18, 18:00 authored by Anna S. Heffron, Sean J. McIlwain, Maya F. Amjadi, David A. Baker, Saniya Khullar, Tammy Armbrust, Peter J. Halfmann, Yoshihiro Kawaoka, Ajay K. Sethi, Ann C. Palmenberg, Miriam A. Shelef, David H. O’Connor, Irene M. OngSera from 40 COVID-19 convalescent patients were assayed for IgG binding to the full SARS-CoV-2 proteome on a peptide microarray. B cell epitopes were defined as peptides in which patients’ average log2-normalized intensity (black lines in line plots) is 2-fold greater than controls’ (gray lines in line plots) and t test statistics yield adjusted p-values <0.1; epitopes are identified by orange shading in the line plots. Data are grouped by their neutralizing titer. COVID-19, coronavirus disease 2019; IgG, immunoglobulin G; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
(XLSX)
History
Usage metrics
Categories
Keywords
peptide sequencesCoV proteinssyndrome coronavirus 2SARS-CoV -2.SARS-CoV -2 infection binduse ultradense peptide microarray m...SARS-CoV -2 infectionreactive B cell epitopesIllness severityenzyme-linked immunosorbent assayCoronavirus membraneSARS-CoV -2humoral immunogensELISAantibody responsesmap 79 B cell epitopes9 SARS-CoV -2 epitopesSARS-CoV -2 proteomeORF 8 proteins1 epitopeORF 3aantibody binding
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC