pgen.1011104.s008.xlsx (9.66 kB)
Annotation coefficients estimated by PolyFun in genome-wide simulations.
dataset
posted on 2023-12-28, 18:29 authored by Wenmin Zhang, Hamed Najafabadi, Yue LiAnnotation coefficients estimated by PolyFun in genome-wide simulations.
History
Usage metrics
Categories
Keywords
widespread linkage disequilibriumunderlying genetic architecturesummarizing posterior probabilitiesreduced computation timepropose effective strategieslevel causal configurationshigh computational costmultiple causal variantsidentifying causal variantsfive functional biomarkersclinically relevant phenotypesthus improve fineintegrating summary statisticsincorporate functional annotationsgenome may helpdiv >< pwide association studiesmapping methods conductingfunctional annotationsprioritize variantsfunctional followbiologically relevantart methodswide utilityuk biobanksparse projectionpossible existenceinformed priorsgenomic locusexhaustive searchestimating hyperparametersefficient finederive functionallyclassical finechallenging duebuild connections
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC