An oral pH-responsive Streptococcus agalactiae vaccine formulation provides protective immunity to pathogen challenge in tilapia

Data related to the Table and figures in the publication (in title)

  

Table 1 shows Particle size measured by dynamic light scattering (mean±SD), n= 12 

Figure 5 shows   the Change in particle size (measured by dynamic light scattering) upon exposure to 0.1M HCl, which is simulating the acidic environment in a fasted tilapia stomach. Means are shown. Error bars reflect the SD. N=12

  

Fig 6 shows the pH measured in the different sections of the gastro- intestinal tract of fasted and fed tilapia (mean ± SD), N=5

  

Fig. 7 Shows the Cumulative percentage mortality in the 3 groups following oral gavage with: (ai) PBS in the negative control group; (aii) Blank Eudragit microparticles; (b) GBS-loaded Eudragit microparticles, and challenge by immersion using a homologous strain of Streptococus agalatiae sequence type on day 21 post-gavage. Error bars represent SD from 4 replicate tanks (25 fish per tank) for each of 3 treatment groups.

The data are shown in Excel files.  Data was collected using dynamic light scattering (Table 1, Figure 5), by measuring pH using a probe (Figure 6), and by counting the numbers of fish which survived the pathogen challenge with time.