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Additional file 5 of Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury

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posted on 2021-09-26, 03:16 authored by Philipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L. H. Carpenter, Mathew R. Guilfoyle, Peter J. A. Hutchinson, Adel Helmy, Eric Peter Thelin
Additional file 5. Title of data: Coefficients and p-values of mixed models. Description of data: There are 12 sheets, with coefficients and p-values of mixed models corresponding to each of Figures 3-4 A-B and Additional file 6. In the 6 sheets containing coefficients, maximum and minimum coefficients for every variable are highlighted at the bottom. Theoretical equivalent increments required in other variables than infection to change their respective concentrations of cytokines with maximum or minimum coefficients by the same amount as a change from 0 to 1 in “infection” are shown. Furthermore, theoretical equivalent increments required in other variables than infection to change the concentrations of cytokines with maximum or minimum infection coefficients by the same amount as a change from 0 to 1 in “infection” are shown. The remaining 6 sheets contain p-values of coefficients of linear mixed effect models. Significant values at p < 0.05 were marked with an asterisk in Figures 3-4 A-B.

Funding

Swedish Brain Foundation Karolinska Institutet Region Stockholm National Institute for Health Research Biomedical Research Centre, Cambridge (Neuroscience Theme; Brain Injury and Repair Theme) National Institute for Health Research (NIHR) NIHR Cambridge Biomedical Research Centre NIHR Global Health Research Group on Neurotrauma a European Union Seventh Framework Program grant (Collaborative European NeuroTrauma Effectiveness Research in TBI [CENTER-TBI]) Royal College of Surgeons of England Royal College of Surgeons of England Pump Priming Grant MRC/Royal of Surgeons of England Clinical Research Training Fellowship MRC Grant Swedish Society for Medical Research StratNeuro Stockholms Läns Landsting Karolinska Institute

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