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Additional file 1 of Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration

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posted on 2024-01-18, 04:40 authored by Christophe Roubeix, Caroline Nous, Sébastien Augustin, Kaitryn E. Ronning, Thibaud Mathis, Frédéric Blond, Pauline Lagouge-Roussey, Sergio Crespo-Garcia, Patrick M. Sullivan, Emmanuel L. Gautier, Nadine Reichhart, José-Alain Sahel, Marie E. Burns, Michel Paques, Torben Lykke Sørensen, Olaf Strauss, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Additional file 1: Table S1. Fold Changes (FC) of the 70 genes upregulated between SplMo and BMMo in scRNAseq experiment. The frequency of Ly6C+Mos in the spleen, in sham Eye and SpleX eye represents the percentage of cells with an expression level > 0 for the selected gene in scRNAseq among the total of Ly6C+Mos in each organ. The Ratio %age Sham vs SpleX eye is the ratio of frequency of Ly6C+Mos in Sham to frequency of Ly6C+Mos in SpleX eye. In red, genes of the spleMdC signature.

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Agence Nationale de la Recherche Institut National de la Santé et de la Recherche Médicale UNADEV BrightFocus Foundation

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