13073_2023_1272_MOESM1_ESM.xlsx (596.56 kB)
Additional file 1 of Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions
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posted on 2024-01-29, 04:40 authored by Shenglin Mei, Adele M. Alchahin, Ioanna Tsea, Youmna Kfoury, Taghreed Hirz, Nathan Elias Jeffries, Ting Zhao, Yanxin Xu, Hanyu Zhang, Hirak Sarkar, Shulin Wu, Alexander O. Subtelny, John Inge Johnsen, Yida Zhang, Keyan Salari, Chin-Lee Wu, Mark A. Randolph, David T. Scadden, Douglas M. Dahl, John Shin, Peter V. Kharchenko, Philip J. Saylor, David B. Sykes, Ninib BaryawnoAdditional file 1: Table S1. Basic information of sample cohort. Table S2. Data quality control metrics. Table S3. Patient sample groups and cell frequency. Table S4. Signature genes for cell annotations. Table S5. List of gene signature score. Table S6. Significant ligand and receptor pairs. Table S7. Cox-regression survival result. Table S8. Flow cytometry panels for myeloid and T cells.
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NHLBI Division of Intramural Research Vetenskapsrådet prostate cancer foundation
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spinal cord compressionopg signaling activitydistinct transcriptional statessolid metastatic tissuestroma cell remodelingcell transcriptomic profilingliquid bone marrowbone marrow stromabone marrow nichetumor samples demonstratedbone metastatic nichehuman metastatic cancerprimary ccrcc tumorsbone marrowmetastatic lesionsccrcc primarycell populationscell datacell analysisbone resorptionbone metastasismetastatic patientsvertebral levelultimately leadingtumor sitetherapeutic targetssurgical fieldstromal subsetstromal microenvironmentspoor progressionoverall survivalone thirdmesenchymal transitionlethal diseaseinvolved ),highly morbidfeaturing increasedexhausted cd8distal ),comprehensive analysiscomparative analysiscommunication channelsbone cellsbenign ).
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