13C-labeling time course of organic acids in the presence or absence of 3MPA.
(A) Relative peak areas of organic acids in the presence (black symbol) or absence (white symbol) of 3MPA. (B) Relative abundances of M, M+1 and M+2 ions characteristic to each organic acid in the presence (3MPA-treated cells, black symbol) or absence (control cells, white symbol) of 3MPA. Values and error bars are the mean and standard deviation from triplicate cultures. Asterisks and daggers indicate statistically significant differences. Red (3MPA treatment) and blue (control) indicate statistically significant differences between 0 min and respective time points for each treatment. Student’s t-test with Bonferroni correction; statistical significance between treatments at each time point (green); Student’s t-test; † p < 0.10, *p < 0.05, **p < 0.01, ***p < 0.001.