<i>spc7-23</i> cells are temperature sensitive and defective in DNA segregation.

<p>(A) The growth of wild type and <i>spc7-23</i> cells on solid media was compared at the indicated temperatures. (B) Cells carrying the mutant <i>spc7-23</i> mutation were incubated at 25°C or 30°C and stained to visualize DNA (blue) and tubulin (green). Note that the DNA segregation becomes unequal at the restrictive temperature.</p>