ß-catenin stabilization is evident in mammary precancers in <i>HER2/neu</i> transgenic mice.

<p>Mammary gland tissue sections from virgin female MMTV/NDL mice were subjected to ß-catenin IHC as previously described <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033421#pone.0033421-Baker1" target="_blank">[43]</a> and counterstained with hematoxylin. As a control, serial sections were stained in parallel omitting primary antibody (right-hand panel). Diffuse cytoplasmic ß-catenin was detected in DCIS-like lesions in MMTV/NDL MGs.</p>