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Verrucarin A increases cancer cell chemosensitivity to other anti-cancer drugs.

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posted on 2014-04-17, 04:12 authored by Fei Yan, Yang Yu, Dar-Chone Chow, Timothy Palzkill, Franck Madoux, Peter Hodder, Peter Chase, Patrick R. Griffin, Bert W. O'Malley, David M. Lonard

(A–D) A549 cells were treated with verrucarin A in combination with gefitinib, BEZ235, gemcitabine, or docetaxel. (E) T-47D cells were treated with verrucarin A in combination with tamoxifen. (F) MDA-MB-231 cells were treated with verrucarin A in combination with paclitaxel. All cells were treated for 72 h, followed by MTS assay.

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