Transient alveolar haemorrhage develops after pristane-injection in both WT and CRAMP^−/− mice.

(A) Classification of lung pathology in pristane-injected mice. Representative images and H&E-stainings of C57BL/6 mice two weeks after pristane-injection, with lungs showing no hemorrhage, partial, or full hemorrhage. Scale bars, 200 µm. (B) Time course of pristane-induced alveolar hemorrhage in WT and CRAMP^−/− mice. Incidence and types of gross pathology at day 0, day 14, and day 180 after pristane-injection. (C) Low mortality after pristane-injection in both CRAMP^+/+ (n = 14) and CRAMP^−/− (n = 15) mice. No significant differences could be found by Logrank test.