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The perinuclear actin cap is not altered in the presence of GFP lamin A Q432X or V415I.

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posted on 2013-08-20, 02:24 authored by Liu Yang, Martina Munck, Karthic Swaminathan, Larisa E. Kapinos, Angelika A. Noegel, Sascha Neumann

C2C12 cells transiently expressing WT GFP lamin A, the mutant proteins Q432X or V415I were stained with DAPI and TRITC phalloidin. The stainings were documented by using a confocal microscope and pictures were taken at the apical plane (red), the mid plane (yelow) and the basal plane (gray). Actin cap fibers are present in control or mutant lamin A expressing cells (long arrow). TRITC phalloidin was present in some GFP lamin A Q432X aggregates (short arrow).

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