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The mechanistic diagram to schematically illustrate the targets of DEK apoptotic action in CRC cells.

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posted on 2014-10-23, 03:30 authored by Lijuan Lin, Junjie Piao, Yibing Ma, Tiefeng Jin, Chengshi Quan, Jienan Kong, Yulin Li, Zhenhua Lin

DEK depletion was accompanied by decreased mutant-p53 and pro-apoptotic protein Bax, which promotes the release of cytochrome C from the mitochondria.

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