Fig_3.tif (514.38 kB)
The effect of simvastatin treatment on the expression of muscle atrophy-related genes, Atrogin-1, MuRF1 and Myostatin.
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posted on 2015-05-28, 02:46 authored by Craig A. Goodman, Derk Pol, Evelyn Zacharewicz, Robert S. Lee-Young, Rod J. Snow, Aaron P. Russell, Glenn K. McConellRats were treated with vehicle (Control) or simvastatin at 60 (Sim 60) and 80 mg.kg-1.day-1 (Sim 80) for 14 days. Muscle mRNA is extracted and analyzed as described in the Methods. mRNA expression was normalised to total cDNA. *—significantly different from Control. Mean ± SEM. n = 6–8/group. One way ANOVA with Newman-Keul’s post-hoc test. P < 0.05.
