The effect of simvastatin treatment on citrate synthase activity, and Cox4 and Cyt C protein expression.

Rats were treated with vehicle (Control) or simvastatin at 60 (Sim 60) and 80 mg.kg^-1.day^-1 (Sim 80) for 14 days. Muscles were collected and subjected to enzyme activity analysis or Western blot analysis with the indicated antibodies as described in the Methods. Protein expression values were normalised to GAPDH and expressed as arbitrary units (AU). Mean ± SEM. n = 8/group. One way ANOVA with Newman-Keul’s post-hoc test.