The change of signal intensity in the irradiated right hemisphere on T2 WI (A, B) correlated well with the gross morphology (C, D) of the sacrificed rabbit at the 48^th week post-irradiation.

It showed mixed signal intensity with a loss of the normal architecture, which presented as radiation necrosis with focal hemorrhage and yellow discoloration in the irradiated right hemisphere (EC = external capsule; HIP = hippocampus; R = right side).