The animal test.

(a) The outline of animal test. (b) The body weights of rats were measured randomly at day 0, 3, 7, 10, and 14. Data are Means ± S, n = 8. No differences in body weight gain were detected among the different experimental groups. (c) The level of serum UA (uric acid), * means P<0.05 compare with control rats, ▵ means P<0.05 compare with hyperuricemic rats, # means P<0.05 compare with allopurinol treated rats, ▾ means P<0.05 compare with DM9218-After group. (d) The level of serum UN (urea nitrogen). (e) The level of serum Cr (creatinine). All values are Means ± S, n = 8.