The alteration of core temperature of mice in the course of hot conditions after berberine (BBR) injection.

A–C: 2 hour time-point after hot conditioning. A: F (3, 36) = 25.901, P<0.001. B: F (3, 36) = 7.922, P<0.001. C: F (3, 36) = 15.916, P<0.001. D–F: half hour time-point of recovery (post-hot conditioning). D: F (3, 36) = 5.952, P = 0.002. E: F (3, 36) = 19.09, P<0.001. F: F (3, 36) = 8.545, P<0.001. Data were presented as mean ± S.D. from ten independent mice (n = 10).