The abundance of the mitochondrial deoxynucleotide (di- and tri- phosphate) transporters is increased in the absence of MPV17.
2016-01-18T15:33:18Z (GMT) by
<p>Representative immunoblot of the equilibrative nucleoside transporter (ENT1) in (<b>A</b>) control and MPV17-mutant fibroblasts in dividing and quiescent cells, and (<b>B</b>) in the liver of wild-type (WT) and knockout (KO) mice. (<b>C</b>) Steady state levels of the mitochondrial deoxynucleotide transporters 1 and 2 (PNC1 and PNC2) in control and MPV1<i>7</i> deficient fibroblasts in proliferating and quiescent conditions. (<b>D</b>) Pnc1 and Pnc2 steady state levels in the liver, of type (WT) and knockout (KO) mice. Vinculin (VCL), and Tom20 were used as loading control.</p>