Figure_5.tif (439.81 kB)
The TCRα LCR drives significant mRNA expression levels of a 3′-linked HLA-B7 reporter gene in B cells.
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posted on 2013-02-20, 22:14 authored by Stefan Knirr, Janette Gomos-Klein, Blanca E. Andino, Faith Harrow, Karl F. Erhard, Damian Kovalovsky, Derek B. Sant'Angelo, Benjamin D. Ortiz(A) Northern blot analyses of RNA prepared from thymocytes and isolated spleen B cells from three independent lines of 1:8-B7 transgenic mice. Thy = Thymus, SpB = Spleen B cells, NTG = non-transgenic. (B) Graph depicting PhosporImager analyses of HLA-B7 reporter expression levels normalized to 18S rRNA. Y-axis values are expressed relative to thymus mRNA levels (designated as 100%).
