Figure_5.tif (4.2 MB)
The MPAKT/Hi-MYC phenotype is characterized by stromal inflammation.
figure
posted on 2011-03-04, 01:09 authored by Nicola J. Clegg, Suzana S. Couto, John Wongvipat, Haley Hieronymus, Brett S. Carver, Barry S. Taylor, Katharine Ellwood-Yen, William L. Gerald, Chris Sander, Charles L. SawyersIHC of VP from mice aged 5–9 weeks, using antibodies to differentiate macrophages (Mac-2), B-lymphocytes (B-220) or T-lymphocytes (CD3). Note periglandular stromal infiltration (arrows) in areas of mPIN, unique to MPAKT/Hi-MYC (right panels) as compared to MPAKT or Hi-MYC. A few macrophages (upper panels) and T-lymphocytes (lower panels) are present within glandular epithelium in mPIN from MPAKT and Hi-MYC (arrowheads). Scale-bars: 50 µm.
