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TSF blocks activation of the NF-κB signaling pathway in DN rats.

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posted on 2016-01-28, 12:42 authored by TingTing Zhao, SiFan Sun, HaoJun Zhang, XiaoRu Huang, MeiHua Yan, Xi Dong, YuMin Wen, Hua Wang, Hui Yao Lan, Ping Li

(A) Immunohistochemistry and semi-quantitative analysis of phosphorylated NF-κB/p65 nuclear location in the glomeruli and tubulointerstitium. Original magnification, × 400. (B) Western blot and semi-quantitative analysis of renal phosphorylation of IκBα and NF-κB/p65 (p-p65). Data are expressed as means ± SE for each group of 9rats.*P<0.05, **P<0.01 TSF-treated group vs. DN group; #P<0.05, ##P< 0.01, ###P<0.001 DN group vs normal group.

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