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TPA+UVC 8-hour gene signature.

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posted on 2015-10-02, 03:26 authored by Kyle P. Glover, Zhongqiang Chen, Lauren K. Markell, Xing Han

(A) A 90 gene signature was derived by determining genes that were significantly altered compared to either stress alone in the time-course experiment (experiment #1) at 8-hours and also expressed in a TPA dose-responsive trend in experiment #2. (B) Visualization of the 90 gene signature based on fold-change in the dose-response experiment revealed the increasing or decreasing expression trends for each gene (each series represented by individual gene in signature) as the concentration of TPA increased from 0.2 nM to 1.0 nM.

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