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"Susceptibility of brain atrophy to TRIB3 in Alzheimer’s disease: evidence from functional prioritization in imaging-genetics": Experimental material
Version 2 2018-02-23, 09:13
Version 1 2018-02-23, 09:05
dataset
posted on 2018-02-23, 09:05 authored by Marco LorenziMarco Lorenzi, Andre AltmannThis collection provides the experimental material associated to the publication "Susceptibility of brain atrophy to TRIB3 in Alzheimer’s disease: evidence from functional prioritization in imaging genetics", accepted for publication in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).
It contains 4 items:
- SNP_list_position.csv
This .csv file provides the list of SNPs analyzed in the work with associated chromosome and position.
- Selection_Probabilities.npy
This is a numpy list generated with Python2.7.
Each element of the list is associated to a PLS component. Each element is a list of 22 arrays, one per chromosome. Each array reports the selection probability associated to each genetic bin. The position (start-end) of each bin is reported in the file SNP_range.npy.
- SNP_range.npy
This is a numpy list generated with Python2.7.
The list contains 22 arrays associated to each chromosome. Each element of the array is a position for the genetic bins used in the analysis.
- genetic_component.npy
This is a numpy list generated with Python2.7.
It contains the 3 genetic components estimated through partial least squares. The dimension of each component is 1167117, corresponding to the number of SNPs analyzed in the study and listed in the file SNP_list_position.csv.
